It is a perennial herb endemic to upper himalayas at an altitude of 26004000 m and spread across various parts of india, china and pakistan 20,74. Saussurea lappa sl has been used as a traditional herbal medicine to treat abdominal pain and tenesmus, and has been suggested to possess various biological activities, including antitumor, antiulcer, antiinflammatory, antiviral, and cardiotonic activities. It was found that both species are really separated from each other through anatomical investigations where the former belong to dicotolydoneae group and the latter to monocotolydoneae. An efficient protocol for in vitro multiplication of saussurea lappa was developed from cotyledonary node explants. Essential oils extracted from the root have been used in traditional medicine and in perfumes since ancient times. Jul 20, 2004 read phytoconstituents from saussurea lappa roots. Modulatory effects of saussurea lappa root aqueous extract against ethephon. Saussurea lappa showed the best antifungal activity. Review of its traditional uses, phytochemistry and pharmacology article pdf available in oriental pharmacy and experimental medicine 121 march 2011 with 5,519 reads. Here, we report on the chemistry of the ethanol and water extracts of s. Antidiabetic effects of arctium lappa are quite encouraging but we still need to know the underlying mechanisms which are regulated by arctium lappa or its bioactive ingredients. Antiulcerogenic activity of saussurea lappa root niranjan sutar, ranju garai, uma shankar sharma, narendra singh and saumendu deb roy department of pharmacy, sir madanlal group of institutions, etawah, upindia abstract the study was designed to investigate the antiulcer activity of ethyl acetate extract of the saussurea lappa root using. Determination of major sesquiterpene lactones in essential oil of inula racemosa and saussurea lappa using qnmr. Our online converter of geospatial pdf format to esri shapefile format pdf to shp is fast and easy to use tool for both individual and batch conversions.
Pdf file created by oracle information rights management irm document protection software. The root of aucklandia lappa decne, family asteraceae, is widely used in asian traditional medicine due to its sesquiterpene lactones. One hundred and eighty buffaloes were used in 18 controlled experiments to compare the efficacy of certain indigenous drugs, including nigella sativa seeds, fumaria parviflora aerial parts, caesalpinia crista seeds, and saussurea lappa roots with triclabendazole against fasciolosis. Rhizomes are used to treat pneumonia, rheumatism, dropsy, urinary diseases, jaundice, skin diseases and leaves are usedto treat mental disorders. The herb excludes the worms found in intestines and other body parts. Wound healing is the process of repair that follows injury of the skin and other soft tissues.
Publication date 1888 usage attributionnoncommercial 3. Department of botany, women university, swabi, guloodheri swabitopi rd, 234302pakistan 2. The sizes of the 17 saussurea plastomes were similar, ranging from 151,474 bp in s. Glucofructans from saussurea lappa roots, chemistry of. Research article open access saussurea lappa extract. Modulatory effects of saussurea lappa root aqueous extract. Pdf chemical composition and pharmacological activities of. Click download or read online button to get the encyclopedia of medicinal plants book now. User just have to provide the list of images and text files, whose contents they want to have in the pdf in a configuration file. Institute of biotechnology and genetic engineering ibge, khyber. Isolated tissue preparations were used to see if the aqueous.
The taxonomy of the genus saussurea in this treatment follows largely the monograph by lipschitz rod saussurea, 1284. Despite significant progress in phytochemical and biological analyses of s. Rapid and efficient extraction and hplc analysis of. The species is endemic to a geographically limited part of the himalayas, and grows on moist slopes at altitudes of 26004000 m. Due to over exploitation for commercial and medicinal purposes, this plant is now endangered. Saussurea lappa has been reported to possess antiatopic properties.
Distribution and comparison of major selected elements in. Subsequently, a new crystalline lactone saussurea lactone c15h20o2rao and verma, 1951 and costunolide were isolated from costus saussurea lappa root oil rao. Clarke, belonging to the family asteraceae and one of the bestknown species within its genus, is a perennial, aromatic, and medicinal plant. Saussurea lappa is a well identified medicinal plant due to its medicinal values commonly this is used in numerous indigenous systems of medicine all over the world. Converter also supports more than 90 others vector and rasters giscad formats and more than 3 000 coordinate reference systems. Costunolide and dehydrocostus lactone were purified from the extract of a herbal medicine, mokko saussurea lappa clarke as active principles that block ctlmediated cytotoxicity 14. Synergistic effect of the methanolic extract of lemongrass with the previous antibiotics against the tested clinical bacterial isolates was determined and the fractional inhibitory concentrations fic of different combination of the extract and the antibiotics were determined. Costunolides, an important sesquiterpene lactone stl isolated from saussurea lappa, are the major pharmaceutical ingredient of various drug formulations. Saussurea costus, commonly known as costus or kuth, is a species of thistle in the genus. Ameliorative effects of saussurea lappa root aqueous.
The hexane extract of saussurea lappa and its active. In china, the hengduan shan area is the center of diversity of saussurea, with more than one hundred species, many of them endemic. Fic index fici was calculated and it was ranged from 0. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. The sequencing and assembly information are provided in tables 1 and additional file 1. Conservation status and therapeutic potential of saussurea. Pdf comparative study of inula racemosa and saussurea. Comparative study of inula racemosa and saussurea lappa on. Saussurea lappa has been used in chinese traditional medicine for the treatment of abdominal pain, tenesmus, nausea, and cancer. The identity of a natural product, erroneously reported as a diterpene alcohol from saussurea lappa clarke, has been established as 22dihydrostigmasterol. Highperformance liquid chromatographic method for quantitative estimation of an antioxidant principle chlorogenic acid in saussarea costus and arctium lappa saussarea costus.
The encyclopedia of medicinal plants download ebook pdf. Saussurea is a genus of about 300 species of flowering plants in the thistle tribe within the daisy family, native to cool temperate and arctic regions of asia, europe, and north america, with the highest diversity in alpine habitats in the himalaya and central asia. Kuth saussurea lappa cultivation in the cold desert environment of the lahaul valley, northwestern himalaya, india. Saussurea costus is effective as a treatment for cough, asthma, bronchitis and cholera. If the inline pdf is not rendering correctly, you can download the pdf file. Arctium lappa is highly appreciated for its health promoting activities. The purpose of denoising is to remove the noise while. The structures of the new compounds have been deduced from spectral data and chemical transformations. Current study was carried out to develop a protocol for micropropagation and to determine morphogenic potential of different. Apr 01, 2015 this page was last edited on 16 december 2019, at 19.
A simple quantitative hplc method has been developed for differentiating two plants of asteraceae family viz. Multiple shoots were induced from cotyledonary nodes. Sesquiterpene lactones from saussurea lappa sciencedirect. Study of hepatoprotective activity of saussurea lappa root.
Study on chemical constituents from roots of saussurea lappa article in zhongguo zhong yao za zhi zhongguo zhongyao zazhi china journal of chinese materia medica 3410. On the chemical composition and antibacterial activity of saussurea. The annual export has been as much as one thousand tons, a large portion used for incense. Allelochemicals are the media of allelopathy and form the chemical bases of plantenvironment interactions. This investigation was undertaken to determine the efficacy of saussurea lappa on wound healing. Confluence of information suggested that arctium lappa was effective against different diseases. Common names include sawwort and snow lotus, the latter used for a number of high altitude species in central asia. Saussurea lappa in the literature, the present study was suggested to evaluate its scientific validity. The black root of saussurea lappa asteraceae, an aromatic perennial plant growing in the open slopes of india and kashmir, are used in traditional medicine. Around 3000 species of saussurea are known, however saussurea lappa clarke which is perennial herb and has been traditionally used as anticancer, antiinflammatory, antiviral, medicine without. As the name of the application suggests, its very simple.
Files are available under licenses specified on their description page. Details about kushta roots, saussurea lappa costus. The plant has been found to possess diverse pharmacological activities. Their structures were determined on the basis of spectral data including 1d and 2d nmr and hreims.
Saussurea lappa clarke is the member of family compositae. All structured data from the file and property namespaces is available under the creative commons cc0 license. We determined the target gene using real time pcr in in vitro experiment. Saussurea lappa clarke compositae is a traditionally known and potent plant which is. Chemical constituents like costunolide, dehydrocostus lactone and cyanopicrin isolated from costus have. Elucidating genes involved in sesquiterpenoid and flavonoid.
May 25, 2014 saussurea lappa sl has been used as a traditional herbal medicine to treat abdominal pain and tenesmus, and has been suggested to possess various biological activities, including antitumor, antiulcer, antiinflammatory, antiviral, and cardiotonic activities. The present study was designed to detect the effect of saussurea lappa and cyperus esculentus extracts on male albino mice fertility in addition to the histopathological changes in liver, kidney and testes. Sm costaceae is an indian ornamental plant which has long been used medicinally in traditional systems of medicine. The current chinese pharmacopoeia reports a monograph for aucklandiae radix, but the extraction method is very long and tedious. In this study, we investigated the effects of hexane extracts of s. Get a printable copy pdf file of the complete article 8. Antimicrobial activity of sesquiterpene lactones isolated. Read download file report abuse chemical, pharmacological and clinical profile of the east asian centella asiatica is a medicinal plant that has been in use since prehistoric times. Asteraceae, an aromatic perennial plant growing in the open slopes of. Saussurea lappa is costus plant from the family of. Study on chemical constituents from roots of saussurea. Saussurea lappa is a pharmacologically important endangered plant enlisted in cites appendix i as well as in nmpb as important species of high trade and stable cultivation.
The effect of sl on breast cancer metastasis, however, is unknown. An endangered medicinal plant zaibunnisa1, safdar hussain shah2, ghulam farooq3, muhammad anwar sajad4 and muhammad anwar saleem khan5 1. The costus saussurea lappa is a wellknown medicinal plant that has been widely used in the traditional medicines in many asian countries. Introduction traditional and folklore medicines play important role in health services around the globe. Saussurea lappa extract suppresses tpainduced cell invasion. Identification of the genes and transcriptional regulation of costunolide biosynthesis pathway in s. Find, read and cite all the research you need on researchgate. Jul 26, 2011 read glucofructans from saussurea lappa roots, chemistry of natural compounds on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Full text full text is available as a scanned copy of the original print version. The results were compared with the standard antifungals. Thymoquinone, an active principle of nigella sativa, inhibited fusarium solani. Main allelochemicals from the rhizosphere soil of saussurea. The aim of this study was the development and optimization of the extraction and analysis of these sesquiterpene lactones. This site is like a library, use search box in the widget to get ebook that you want.
The structure, bioactivity, saussurea lappa and likely mechanisms of action of s. The treatment of bronchial asthma with saussurea lappa. Alantolactone from saussurea lappa exerts antiinflammatory. Clarke has been used in folk medicine for the treatment of various ailments and diseases such as viz. Their structures were determined spectroscopically to be cynaropicrin 1, arguerin b 2, cebellin f 3, 8. The aromatic root of this tall perennial, native to kashmir, at altitudes of 8,000 to 12,000 feet, is of medicinal value. Yang hui 1, xie jinlun 1, sun handong 2 1chemistry department of yunnan university, kunming 650091 2 laboratory of phytochemistry, kunming institute of botany, chinese academy of sciences, kunming 650204. Sesquiterpenoids from costus root oil saussurea lappa.
As an effective expectorant, it helps to treat asthma by making breathing easier, clearing and relaxing bronchiole. Cytotoxic sesquiterpene lactones from saussurea calcicola. Seven sesquiterpene lactones were isolated by the chromatographic separation of the meoh extract of the aerial parts ofsaussurea calcicola compositae. It is a major advancement of tlc principle with short time duration and better resolution. Chemical constituents like costunolide, dehydrocostus lactone and cyanopicrin isolated from costus have been documented to have more ability to be. Kuth saussurea lappa cultivation in the cold desert environment. To determine true allelochemicals and their autotoxic effects, seven compounds were isolated and identified from insitu sampled rhizosphere soil of cultivated saussurea lappa. Clarke family asteraceae kuth is a robust erect, perennial plant with large leaves. Potential antidiabetic and antioxidant activities of a. It saves the document in a sealed, or locked, format and can only be opened by users with sufficient rights.
Verifying the scientific name of costus saussurea lappa. This page was last edited on 16 december 2019, at 19. Saussurea costus synonymous with saussurea lappa, locally known as kuthis a robust perennial herb of the western himalayas, distributed in pakistan and india. Synergistic effect of the methanolic extract of lemongrass.
Field trial of saussurea lappa roots against nematodes and nigella sativa seeds against cestodes in children. Alantolactone from saussurea lappa exerts antiinflammatory effects by inhibiting chemokine production and stat1 phosphorylation in tnf and. Caffeoylquinic acid derivatives from the roots of arctium. Three new guaianolides, namely 11, epoxydehydrocostuslactone, 11, epoxyisozaluzanin c and 11, epoxy3keto dehydrocostuslactone were isolated from the petrol extract of powdered costus roots saussurea lappa. Cell migration and invasion are crucial in neoplastic metastasis. Saussurea lappaextract was prepared by maceration of 50 gm of saussurea lapparoots with 90% methanol, then chemical detection of. Us2946783a preparation of costus root oil and the products. Image denoising is an important preprocessing task which is used before further processing of image. Comparative study of inula racemosa and saussurea lappa on the glucose level in albino rats. Saussurea costus, commonly known as costus or kuth, is a species of thistle in the genus saussurea native to india. Inula racemosa and saussurea lappa have been used in ayurvedic system for the management of diabetes. Determination of major sesquiterpene lactones in essential. Download pdf pakistan journal of agricultural sciences. Saussurea lappa is a medicinal plant, which is used against a lot of diseases.
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